The potent phytochemical known as cannabidiol is a phytocannabinoid derived from the industrial plant Cannabis Sativa L. It has many recently discovered healing properties that in fact can be used in order to help alleviate a host of abnormalities.
The host of health benefits of hemp and particularly CBD oil listed below:
- Pain and Inflammation
- Antioxidant and Neuroprotectant
- Reliever of compulsive addiction and opioid drugs
- Sleep aid for REM sleep disorder
- Wakefulness aid for daytime sleepiness
- Anxiolytic aid for relieving anxiety and mood booster for depression
- Critical aid in lipid signaling and metabolic effects with diabetes complications
- Therapeutic potential for cancer, obesity, neurodegenerative, and cardiovascular diseases
- Therapeutic potential for epilepsy and multiple sclerosis
In addition to what’s mentioned above. CBD is noted to boost memory, combat inflammation, and increase restful sleep.
Many are hesitant to try CBD oil derived from the flowers of industrial hemp plants. This is mainly due to its close resemblance to it’s relatives Cannabis Ruderalis, Cannabis Sativa, and Cannabis Indica which are higher in the psychoactive phytochemical THC (Delta-9-Tetrahydrocannabinol). Although Cannabis Sativa L is a close relative of Indica and Sativa, it does not have more than .3% THC which is the main psychoactive property that produces that noted “euphoric high” that people often associate with cannabis.
It is important to note that Industrial hemp is Cannabis Sativa L. The relative Cannabis Ruderalis is native to Eastern Europe and Russia and also happens to be lower in THC content.
There is a lot of promising medical research backing up CBD oil which can make it an excellent alterative treatment for many people across the globe due to its ability to affect the Endocannabinoid system inside the human body.
The hemp plant contains antioxidants known as cannabinoids. These molecules help assist with oxidative diseases known as ischemic, age-related, inflammatory, and autoimmune diseases. CBD oil is actually known to be neuroprotective which means that it helps protect the brain against future development of Alzheimer’s disease, dementia, and Parkinson’s disease.
CBD is also coming to the light as a very powerful anti-inflammatory molecule that targets T-cells in the body and induces apoptosis and suppresses cytokines and chemokines. This is extremely noteworthy due to the anti inflammatory CB2 receptors that are activated and beneficial for reducing leukocyte endothelial interactions, and prevent further inflammatory damage.
One of the most exciting potential roles of CBD oil is its ability to assist those who are affected by addiction and particularly opioid addiction. CBD is shown to be an agonist of 5-HTI a serotoninergic receptor that regulates stress response and compulsive behaviors. This is promising due to the high risks associated with addictions and the toxicity of opioid drugs on the body and specifically the liver. CBD has also shown that it can indirectly be useful in treating addiction, protect against stress vulnerability and neurotoxicity.
Endocannabinoids are made from essential fatty acids from within the diet. It is critical for our bodies to have cannabinoids circulating in order to help the body maintain stability and overall wellness as part of homeostasis.
The Endocannabinoid system regulates all other body systems and creates homeostasis within the body. It has a tendency to assist with function and strength. The importance of this action is highlighted within the immune system, and within the heart where regulation of blood pressure via receptors in the walls of the arteries, and blood sugar via insulin release, and regulation of body temperature through the hypothalamus. The Endocannabinoid system is located within the immune and nervous system.
The central nervous system happens to contain CB1 receptors within the brain and digestive system. The lymph system, spleen, skin, immune cells, and reproductive organs all contain CB2 receptors. These receptors act and link with G protein receptors throughout the body and cause cells to trigger immunity and control inflammation in the body. This is critical as it helps endocannabinoids act as neurotransmitters in order to create balance.
Through the process of retrograde neurotransmission endocannabinoids go inside the synapse and become neurotransmitters by activating CB1 or CB2 receptors on presynaptic axons. These are some of the most abundant receptors within the brain for controlling inflammation.
The endocannabinoid system uses CBD to heal itself and achieve a state of homeostasis, thus making it tremendously valuable as a medicinal application. If you’re interested in trying CBD oil from a pure quality sourced from a third party tested source try out The Hemp Farmacy.
Be sure to take note of CBD oil as it starts to steadily incline in popularity as a form of healthy supplement.
Works Cited:
- Attila Olah et al. Targeting Cannabinoid Signaling in the Immune System: “High”-ly Exciting Questions, Possibilities, and Challenges. Front Immunol. 2017; 8: 1487.
- Caroline Turcotte. The CB2 receptor and its role as a regulator of inflammation. Cell Mol Life Sci J. 2016; 73(23): 4449-4470.
- Murillo-Rodríguez, Eric et al. “Potential Effects of Cannabidiol as a Wake-Promoting Agent.” Current Neuropharmacology 12.3 (2014): 269–272. PMC. Web. 13 Sept. 2018.
- Nagarkatti, Prakash et al. “Cannabinoids as Novel Anti-Inflammatory Drugs.” Future medicinal chemistry 1.7 (2009): 1333–1349. PMC. Web. 14 Sept. 2018.
- Oleson, Erik B., and Joseph F. Cheer. “A Brain on Cannabinoids: The Role of Dopamine Release in Reward Seeking.” Cold Spring Harbor Perspectives in Medicine 2.8 (2012): a012229. PMC. Web. 14 Sept. 2018.
- Patricia H. Reggio. Endocannabinoid Binding to the Cannabinoid Receptors: What Is Known and What Remains Unknown. Curr Med Chem J. 2010; 17(14): 1468-1486.
- Prud’homme, Mélissa, Romulus Cata, and Didier Jutras-Aswad. “Cannabidiol as an Intervention for Addictive Behaviors: A Systematic Review of the Evidence.” Substance Abuse: Research and Treatment 9 (2015): 33–38. PMC. Web. 14 Sept. 2018.
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